STUDIES ON THE MECHANISM OF ALLOXAN HYPOGLYCEMIA
نویسندگان
چکیده
منابع مشابه
Studies on the mechanism of alloxan hypoglycemia.
It is well known that when alloxan is injected intravenously into rabbits, dogs, and monkeys an initial hyperglycemia is followed by a transient hypoglycemia, leading to death of the animals from hypoglycemic convulsions. If the hypoglycemia is prevented by repeated intravenous injections of glucose, the animals survive and permanent hyperglycemia and diabetes develop. The cause of the transien...
متن کاملOn the Mechanism of Alloxan Hypoglycemia
Intravenous injection of alloxan into rabbits, rats, dogs, monkeys, etc., produces a brief hyperglycemia, then a transient hypoglycemia, which in the case of rabbits is severe enough to cause convulsions and death, unless counteracted by repeated injections of glucose, and finally a permanent diabetic hyperglycemia. The cause of the transient hypoglycemia has had various explanations. Goldner a...
متن کاملOn the Mechanism of Alloxan Hypoglycemia
Intravenous injection of alloxan into rabbits, rats, dogs, monkeys, etc., produces a brief hyperglycemia, then a transient hypoglycemia, which in the case of rabbits is severe enough to cause convulsions and death, unless counteracted by repeated injections of glucose, and finally a permanent diabetic hyperglycemia. The cause of the transient hypoglycemia has had various explanations. Goldner a...
متن کاملStudies on the Mechanism of Ethanol-induced Hypoglycemia
Hypoglycemia after ingestion of ethanolic beverages has been reported (1-4). In some cases (1, 2), hypoglycemia was attributed to the nonethanol ingredients in such mixtures as "smoke" and "solox" (methyl alcohol, and gasoline and ethyl acetate). Cummins, however, suggested that hypoglycemia might be caused by ethanol itself (3). He described a 6-year-old boy who had convulsions and hypoglycemi...
متن کاملStudies on the Relationship of Alloxan-diabetes
A reduction in the size and incidence of tumors has been shown to occur in alloxanized Wistar rats given injections intraperi@oneally of homogenates of the transplantable Novikoff hepatoma (9, 10). Salzberg and Griffin (@6)likewise demonstrated a reduction in the incidence of DAB-induced hepa tomas in alloxanized rats, and Vangerov and Mc Kee (80) have recently reported a diminution in the grow...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1948
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)57210-0